Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192482 | 0.88 | RAB9A (0.44) | ALDH1A1HPGDKMT2ANPC1RAB9A | |
| SCHEMBL5901959 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPK1PKMKMT2A | |
| SCHEMBL9685711 | 0.85 | POLB (0.50) | ALDH1A1HPGDMAPK1NPC1RAB9A | |
| SCHEMBL9687520 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL9686345 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9686578 | 0.83 | HPGD (0.45) | ALDH1A1HPGDMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL9687443 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL9686504 | 0.81 | SMN1; SMN2 (0.69) | ALDH1A1HPGDSMN1; SMN2PKMKMT2A | |
| SCHEMBL6378056 | 0.79 | FAAH (0.43) | ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL7462025 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4920129-A | Anti-ulcerative imidazopyridine compounds | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0308917-A2 | Imidazopyridine compound, a process for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |