Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687037 | 0.88 | NPC1 (0.72) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL5853278 | 0.86 | NPC1 (1.00) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL9686499 | 0.84 | ALDH1A1 (0.57) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4650207 | 0.83 | NPC1 (0.58) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL9694548 | 0.82 | HPGD (0.47) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9687318 | 0.82 | NPC1 (0.76) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL10489837 | 0.82 | NPC1 (0.76) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL29955456 | 0.80 | NPC1 (0.72) | NPC1RAB9ACASP3L3MBTL1ALDH1A1 | |
| SCHEMBL8576011 | 0.80 | NLRP3 (0.46) | NPC1RAB9AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8175962 | 0.79 | RAB9A (0.46) | NPC1RAB9AALDH1A1POLBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |