Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685814 | 0.83 | TERT (0.44) | NMT1HDAC1HDAC6HDAC4BRD4 | |
| SCHEMBL9686626 | 0.76 | HDAC4 (0.41) | HDAC1HDAC6HDAC4BRD4GRM5 | |
| SCHEMBL8127407 | 0.76 | ATAD2 (0.56) | BRD4L3MBTL1SLC5A1SLC5A2TSHR | |
| Hydrochloric Acid SCHEMBL20703948 | 0.75 | ATAD2 (0.55) | BRD4GAAL3MBTL1SLC5A1SLC5A2 | |
| SCHEMBL30806610 | 0.74 | PIK3CG (0.52) | BRD4L3MBTL1TSHRF10HTT | |
| SCHEMBL27378235 | 0.74 | PIK3CG (0.52) | BRD4L3MBTL1TSHRF10HTT | |
| SCHEMBL29978712 | 0.74 | BRD4 (0.57) | BRD4L3MBTL1TSHR | |
| SCHEMBL758149 | 0.74 | BRD4 (0.57) | BRD4L3MBTL1TSHR | |
| SCHEMBL18226834 | 0.74 | CHRM1 (0.42) | BRD4TSHRHTTCHRM1 | |
| SCHEMBL16522709 | 0.74 | CHRM1 (0.47) | BRD4TSHRHTTCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |