Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687722 | 0.90 | HDAC4 (0.39) | HDAC4HDAC1HDAC6HTTTSHR | |
| SCHEMBL9686613 | 0.81 | BRD4 (0.43) | HTTTSHRBRD4PLK1PIK3CG | |
| SCHEMBL9832981 | 0.78 | HTT (0.49) | HTTTSHRBRD4PLK1PIK3CG | |
| SCHEMBL9686469 | 0.76 | NMT1 (0.41) | HDAC4HDAC1HDAC6HTTTSHR | |
| SCHEMBL9831606 | 0.76 | PLK1 (0.45) | HTTTSHRBRD4PLK1PIK3CG | |
| SCHEMBL9831062 | 0.76 | HTT (0.44) | HTTTSHRBRD4PLK1USP2 | |
| SCHEMBL9685814 | 0.73 | TERT (0.44) | HDAC4HDAC1HDAC6TSHRBRD4 | |
| SCHEMBL9687032 | 0.69 | BRD4 (0.36) | HTTTSHRBRD4PIK3CGSLC5A1 | |
| SCHEMBL9687661 | 0.65 | BRD4 (0.54) | HDAC1HDAC6TSHRBRD4PIK3CG | |
| SCHEMBL24258037 | 0.65 | HDAC1 (0.61) | HDAC4HDAC1HDAC6TSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| US-5077401-A | Herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-4902335-A | Benzo-fused cyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-02-20 | — | — | US | disclosed |