Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560687 | 0.87 | LTA4H (0.56) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL3665962 | 0.83 | RAB9A (0.55) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL1002382 | 0.80 | LTA4H (0.59) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL10562118 | 0.80 | NPC1 (0.59) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL9890 | 0.79 | — | — | |
| SCHEMBL16237691 | 0.78 | CHRNB2 (0.47) | NPC1RAB9APLAUPTPN1DCPS | |
| Bromide SCHEMBL5755866 | 0.78 | RAB9A (0.57) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 | |
| SCHEMBL16054964 | 0.77 | CHRNB4 (0.50) | NPC1RAB9ASMN1; SMN2PLAUL3MBTL1 | |
| SCHEMBL1445524 | 0.77 | S1PR4 (0.47) | NPC1RAB9ASMN1; SMN2HTTPLAU | |
| SCHEMBL1921438 | 0.77 | LTA4H (0.56) | NPC1RAB9ALTA4HMAPK14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102443009-B | Fused ring kinase inhibitor | KBP BIOSCIENCES CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102443009-A | Fused ring kinase inhibitors | KBP BIOSCIENCES CO LTD | 2012-05-09 | — | — | CN | disclosed |
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4782055-A | Imidazopyridine compounds useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| CN-87108027-A | Imidazopyridine and preparation method thereof | — | 1988-06-08 | — | — | CN | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| EP-0228006-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |