Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003878 | 0.83 | CYP3A4 (0.71) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL30833308 | 0.83 | CYP3A4 (0.71) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL7098921 | 0.81 | CYP3A4 (0.69) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| Propanil SCHEMBL26871 | 0.81 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL4004069 | 0.81 | CYP3A4 (0.69) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| Propanil SCHEMBL1702271 | 0.81 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL7932797 | 0.81 | CYP3A4 (0.69) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| SCHEMBL15107476 | 0.81 | L3MBTL1 (0.74) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| Propanil SCHEMBL21900164 | 0.81 | CYP3A4 (1.00) | CYP3A4EPHX1EPHX2MAPTNPSR1 | |
| Propanil SCHEMBL634840 | 0.80 | CYP3A4 (0.96) | CYP3A4EPHX1EPHX2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476760-A2 | 4-substituted isoxazole herbicides | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |