Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349434 | 1.00 | CA12 (0.57) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL22783671 | 0.87 | PPARA (0.53) | CA12CA1CA2CA9MMP13 | |
| SCHEMBL4456622 | 0.86 | CA12 (0.55) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL4456625 | 0.86 | CA12 (0.55) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL7283452 | 0.86 | CTSK (0.54) | MMP13PPARACASP1PPARGCTSK | |
| SCHEMBL2749553 | 0.86 | PPARA (0.53) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL12226071 | 0.85 | MMP13 (0.51) | CA12CA1CA2CA9ITGB3 | |
| SCHEMBL10603735 | 0.85 | SYK (0.54) | CA12CA1CA2CA9MMP13 | |
| SCHEMBL6841173 | 0.84 | CA1 (0.58) | CA12CA1CA2CA9CTSK | |
| SCHEMBL30630026 | 0.84 | CA1 (0.58) | CA12CA1CA2CA9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191989-B1 | ANTIBIOTIC ISOXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |