Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 6/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687753 | 0.89 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9686860 | 0.88 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9686951 | 0.87 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9687439 | 0.87 | DPP4 (0.54) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9687767 | 0.83 | DPP4 (0.51) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL10551772 | 0.82 | DPP4 (0.51) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL9686526 | 0.81 | LMNA (0.56) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL8435331 | 0.80 | ALDH1A1 (0.66) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9687424 | 0.80 | DPP4 (0.66) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9775909 | 0.79 | KCNH2 (0.56) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | claimed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |