Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | CLK2 | P49760 | 1/20 | 0.63 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | DPP4 | P27487 | 6/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687424 | 0.89 | DPP4 (0.66) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9686854 | 0.89 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9687790 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL311935 | 0.87 | LMNA (0.68) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9686438 | 0.87 | DPP4 (0.68) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9685613 | 0.86 | DPP4 (0.68) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9685551 | 0.85 | LMNA (0.55) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL9775909 | 0.85 | KCNH2 (0.56) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL10928412 | 0.84 | DPP4 (0.64) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL10549780 | 0.84 | DPP4 (0.59) | KDM4EHSD17B10ALDH1A1HPGDDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0160578-B1 | 1,8-NAPHTHYRIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-11-23 | — | — | EP | claimed |
| JP-63099070-A | — | — | None | — | — | JP | disclosed |
| JP-60172981-A | — | — | None | — | — | JP | disclosed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0160578-B1 | 1,8-NAPHTHYRIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| JP-S6399070-A | 1,8-NAPHTHYRIDINE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1988-04-30 | — | — | JP | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0160578-A1 | 1,8-Naphthyridine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| JP-S60172981-A | 1,8-NAPHTHYRIDINE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1985-09-06 | — | — | JP | disclosed |