Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780298 | 0.78 | NPC1 (0.48) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL13539167 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL26764530 | 0.76 | SHBG (0.61) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL4662645 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL1619364 | 0.76 | TAAR1 (0.60) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL186541 | 0.76 | CNR1 (0.42) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL7039179 | 0.76 | MEN1 (0.50) | SMN1; SMN2MEN1KMT2ANPC1MAPK1 | |
| SCHEMBL5781869 | 0.76 | RAB9A (0.38) | SMN1; SMN2MEN1KMT2ANPC1MAPT | |
| SCHEMBL9686932 | 0.76 | KCNN4 (0.40) | SMN1; SMN2NPC1MAPK1RAB9AKCNN4 | |
| SCHEMBL2313147 | 0.75 | TAAR1 (0.58) | KMT2AMAPTMAPK1HTTKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |