Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9630643 | 0.92 | MEN1 (0.42) | MEN1KMT2ATP53ALDH1A1SSTR4 | |
| Oxalic Acid SCHEMBL9630637 | 0.92 | MEN1 (0.42) | MEN1KMT2ATP53ALDH1A1SSTR4 | |
| Noberastine SCHEMBL18424 | 0.88 | NR4A2 (0.45) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL9629623 | 0.87 | WHR1 (0.39) | NPC1RAB9AMEN1KMT2ATSHR | |
| Fumaric Acid SCHEMBL9629725 | 0.87 | MEN1 (0.41) | MEN1KMT2ATP53ALDH1A1SSTR4 | |
| SCHEMBL9629492 | 0.86 | MEN1 (0.41) | MEN1KMT2ATP53ALDH1A1SSTR5 | |
| SCHEMBL9630536 | 0.86 | MEN1 (0.42) | MEN1KMT2ATP53ALDH1A1SSTR5 | |
| SCHEMBL9630210 | 0.86 | EED (0.39) | NPC1RAB9AMEN1KMT2ATSHR | |
| SCHEMBL9687543 | 0.85 | NOS2 (0.52) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL14198334 | 0.85 | TSHR (0.52) | NPC1RAB9AMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295742-B1 | NOVEL N-(4-PIPERIDINYL) BICYCLIC CONDENSED 2-IMIDAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-08-26 | — | — | EP | claimed |
| US-4897401-A | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases | JANSSEN PHARMACEUTICAL N.V. (BE) | 1990-01-30 | — | — | US | claimed |
| EP-0295742-A1 | Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-21 | — | — | EP | claimed |
| US-5006527-A | Antihistamines, antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-09 | — | — | US | disclosed |
| US-4897401-A | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases | JANSSEN PHARMACEUTICAL N.V. (BE) | 1990-01-30 | — | — | US | disclosed |
| EP-0295742-A1 | Novel N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |
| JP-1025776-A | — | — | 0001-01-01 | — | — | JP | disclosed |