Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | GPR4 | P46093 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687066 | 0.87 | RET (0.39) | MEN1KMT2AEHMT2DNMT1ALDH1A1 | |
| Oxalic Acid SCHEMBL9630637 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL9630536 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL9629492 | 0.85 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTTP53 | |
| Oxalic Acid SCHEMBL9630643 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL9630539 | 0.83 | NOS2 (0.48) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL9630174 | 0.83 | MEN1 (0.39) | MEN1KMT2AEHMT2DNMT1ALDH1A1 | |
| Noberastine SCHEMBL18424 | 0.83 | NR4A2 (0.45) | MEN1KMT2AALDH1A1MAPTTP53 | |
| Oxalic Acid SCHEMBL9807286 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTTP53 | |
| Oxalic Acid SCHEMBL9807288 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151424-A | Antiallergens or antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-29 | — | — | US | disclosed |
| EP-0297661-B1 | [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-09-16 | — | — | EP | disclosed |
| US-4988689-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-01-29 | — | — | US | disclosed |
| EP-0297661-A1 | [(Bicyclic heterocyclyl)methyl and -hetero] substituted hexahydro-1H-azepines and pyrrolidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-01-04 | — | — | EP | disclosed |