Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162529 | 0.83 | OPRM1 (0.56) | PTGS2ALDH1A1MAPK10SRCHPGD | |
| SCHEMBL6166055 | 0.79 | ALDH1A1 (0.46) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL6167303 | 0.78 | ALDH1A1 (0.45) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL6165988 | 0.78 | ALDH1A1 (0.45) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL6165127 | 0.78 | ALDH1A1 (0.43) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL5698532 | 0.78 | PTGS2 (0.64) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL6162867 | 0.76 | ALDH1A1 (0.49) | PTGS2PTGS1ALDH1A1MAPK10SRC | |
| SCHEMBL16516850 | 0.71 | ALDH1A1 (0.41) | PTGS2ALDH1A1MAPK10SRCHPGD | |
| SCHEMBL23657754 | 0.70 | PTGS1 (0.47) | PTGS2PTGS1ALDH1A1HPGDKMT2A | |
| SCHEMBL6163485 | 0.70 | ALDH1A1 (0.38) | PTGS2PTGS1ALDH1A1MAPK10SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079258-A | Enzyme inhibitors, antiallergens treatment of asthma | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | claimed |
| US-5104442-A | Cereals | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0470489-A1 | 4,5,6,7-Tetrahydro-3-aryl-indazoles, process for their preparation and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-12 | — | — | EP | disclosed |