Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | EBP | Q15125 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687813 | 0.83 | ABCB1 (0.42) | DRD2CHRM2ADRA2ACHRM1ADRA2B | |
| SCHEMBL9687108 | 0.74 | SMPD3 (0.33) | DRD2 | |
| SCHEMBL9688429 | 0.70 | OPRD1 (0.40) | DRD2CHRM2CHRM1CHRM4SLC6A4 | |
| SCHEMBL9686539 | 0.68 | DRD2 (0.48) | DRD2 | |
| SCHEMBL29217928 | 0.67 | DRD2 (0.47) | DRD2 | |
| SCHEMBL22068058 | 0.67 | DRD2 (0.45) | DRD2SIGMAR1TMEM97KCNH2 | |
| SCHEMBL29217925 | 0.66 | DRD2 (0.46) | DRD2 | |
| SCHEMBL1896048 | 0.66 | DRD2 (0.44) | DRD2 | |
| SCHEMBL19490649 | 0.66 | DRD2 (0.46) | DRD2TMEM97 | |
| SCHEMBL29622676 | 0.66 | DRD2 (0.46) | DRD2TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |