Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687111 | 0.83 | DRD2 (0.40) | ABCB1HTR3EHTR3BCHRM2ADRA2A | |
| SCHEMBL9688429 | 0.80 | OPRD1 (0.40) | CHRM2CHRM1DRD2SLC6A4 | |
| SCHEMBL22068058 | 0.71 | DRD2 (0.45) | DRD2SIGMAR1TMEM97 | |
| SCHEMBL6796838 | 0.71 | SIGMAR1 (0.57) | DRD2HRH1SIGMAR1SPHK1HRH3 | |
| SCHEMBL6796835 | 0.71 | SIGMAR1 (0.57) | DRD2HRH1SIGMAR1SPHK1HRH3 | |
| SCHEMBL13493065 | 0.71 | GAA (0.45) | SPHK1HRH3LTA4HSLC6A4 | |
| SCHEMBL19043430 | 0.71 | GAA (0.45) | SPHK1HRH3LTA4HSLC6A4 | |
| SCHEMBL13108574 | 0.71 | GAA (0.45) | SPHK1HRH3LTA4HSLC6A4 | |
| SCHEMBL9687809 | 0.70 | MCHR1 (0.34) | DRD2 | |
| SCHEMBL20553932 | 0.69 | KDM4E (0.53) | ADRA2ADRD2HTR2AHTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |