Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575392 | 0.81 | L3MBTL1 (0.60) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL10094614 | 0.81 | CYP2A6 (0.61) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL22660623 | 0.81 | HSD17B1 (0.55) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL1422442 | 0.79 | EPHB4 (0.55) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL13575394 | 0.79 | OXTR (0.53) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL3168495 | 0.79 | CYP2A6 (0.51) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL3176320 | 0.78 | CYP2A6 (0.58) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL15563751 | 0.78 | CYP2A6 (0.50) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL5820464 | 0.77 | HSD17B1 (0.51) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 | |
| SCHEMBL10094329 | 0.77 | CYP2A6 (0.49) | CYP2A6HSD17B1HSD17B2JAK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |