Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397511 | 0.81 | CA1 (0.47) | CA2CA9CA1 | |
| SCHEMBL23449 | 0.76 | MMP2 (0.44) | CA2CA9CA1STS | |
| SCHEMBL3192131 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL18744789 | 0.73 | SMN1; SMN2 (0.39) | CA2CA9CA1STS | |
| SCHEMBL499083 | 0.72 | CXCR2 (0.41) | CA2CA9CA1 | |
| SCHEMBL1008446 | 0.72 | MMP2 (0.48) | CA2STS | |
| SCHEMBL18361466 | 0.71 | CA1 (0.40) | CA2CA9CA1STS | |
| SCHEMBL18361467 | 0.71 | MMP14 (0.45) | CA2CA9CA1 | |
| SCHEMBL23650 | 0.71 | MMP2 (0.40) | CA2CA9CA1 | |
| SCHEMBL19204140 | 0.70 | STS (0.45) | CA2CA9CA1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |