Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1157615 | 0.92 | HTT (0.54) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL2076302 | 0.92 | HTT (0.54) | HTTTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6823722 | 0.88 | HTT (0.59) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL6825987 | 0.88 | HTT (0.59) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL61078 | 0.88 | ALDH1A1 (0.51) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL62955 | 0.88 | ALDH1A1 (0.50) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL16098596 | 0.86 | TDP1 (0.60) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL18359615 | 0.86 | S1PR4 (0.48) | HTTTDP1ALDH1A1CYP3A4LMNA | |
| SCHEMBL6823725 | 0.85 | HTT (0.45) | HTTALDH1A1CYP3A4LMNATSHR | |
| SCHEMBL6823093 | 0.81 | KMT2A (0.56) | HTTALDH1A1LMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |