Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153952 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL8895191 | 0.91 | ALDH1A1 (0.39) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL9687110 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL9152929 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL9154264 | 0.78 | TRPV4 (0.39) | MAPK1TRPV4 | |
| SCHEMBL27623466 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL19021269 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL31609232 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL28657820 | 0.75 | MEN1 (0.50) | ALDH1A1MEN1TP53CYP3A4MAPT | |
| SCHEMBL17265819 | 0.74 | MAPK1 (0.39) | ALDH1A1MEN1TP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162584-A | FLUOROBENZENE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-10 | — | — | US | disclosed |
| EP-0415595-A1 | Fluorobenzene derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-06 | — | — | EP | disclosed |