Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | BID | P55957 | 4/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992770 | 0.85 | CD44 (0.39) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL30645118 | 0.85 | CD44 (0.39) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL2857705 | 0.83 | CYP3A4 (0.46) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL6931597 | 0.82 | CYP3A4 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL19429809 | 0.82 | CYP3A4 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL5500412 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL3482721 | 0.80 | CD44 (0.46) | ALDH1A1CYP3A4CD44ALOX15TSHR | |
| SCHEMBL9687584 | 0.80 | CD44 (0.35) | ALDH1A1CYP3A4CD44BIDMCL1 | |
| SCHEMBL4763408 | 0.80 | BID (0.47) | KDM4EMAPTBIDMCL1BCL2L1 | |
| SCHEMBL9688931 | 0.80 | CA2 (0.37) | KDM4EALDH1A1CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |