Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931597 | 1.00 | CYP3A4 (0.44) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2857705 | 0.98 | CYP3A4 (0.46) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL723196 | 0.91 | ALDH1A1 (0.43) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29573041 | 0.91 | ALDH1A1 (0.43) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9992854 | 0.89 | CYP3A4 (0.42) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| SCHEMBL23159817 | 0.89 | SIGMAR1 (0.46) | CYP3A4MAPTALDH1A1SIGMAR1LIPG | |
| SCHEMBL23159850 | 0.87 | ALOX15 (0.47) | CYP3A4MAPTALDH1A1SIGMAR1LIPG | |
| SCHEMBL2178352 | 0.84 | LIPG (0.47) | LIPGCA2MGLLSLC6A4BCHE | |
| Methyl Carbamate SCHEMBL28108898 | 0.83 | CYP4A11 (0.43) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 | |
| Carbamic Acid SCHEMBL28108896 | 0.82 | SIGMAR1 (0.41) | CYP3A4MAPTKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313816-B1 | METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE | OMEICOS THERAPEUTICS GMBH (DE) | 2023-05-24 | — | — | EP | disclosed |
| US-20210353569-A1 | Analogs of CYP-Eicosanoids for Use in Treating or Preventing a Disorder Associated with Neovascularization and/or Inflammation | OMEICOS THERAPEUTICS GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| US-20190133976-A1 | METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE | OMEICOS THERAPEUTICS GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| US-20190117597-A1 | ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION | MAX DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2019-04-25 | — | — | US | disclosed |
| WO-2017168007-A1 | ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION | OMEICOS THERAPEUTICS GMBH (DE) | 2017-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353569-A1 | Analogs of CYP-Eicosanoids for Use in Treating or Preventing a Disorder Associated with Neovascularization and/or Inflammation | ALOX5, ALOX15B, ALOX15 | CYP3A4 111/4885MAPT 4420/4885KDM4E 3945/4885 |
| US-20190117597-A1 | ANALOGS OF CYP-EICOSANOIDS FOR USE IN TREATING OR PREVENTING A DISORDER ASSOCIATED WITH NEOVASCULARIZATION AND/OR INFLAMMATION | ALOX5, ALOX15B, ALOX15 | CYP3A4 111/4885MAPT 4420/4885KDM4E 3945/4885 |
| US-20190133976-A1 | METABOLICALLY ROBUST ANALOGS OF CYP-EICOSANOIDS FOR THE TREATMENT OF CARDIAC DISEASE | ALOX5, ALOX15, ALOX15B | CYP3A4 112/4885MAPT 4771/4885KDM4E 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.