Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 3/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | GMPS | P49915 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517351 | 1.00 | ADORA2A (0.47) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9687595 | 0.69 | PI4KA (0.54) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9687602 | 0.69 | PI4KA (0.54) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL23969763 | 0.68 | PI4K2A (0.56) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL9023387 | 0.67 | GMPS (0.49) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL10649999 | 0.67 | PI4K2A (0.51) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL30382315 | 0.65 | ADORA2A (0.52) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL8590840 | 0.65 | ADORA3 (0.52) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL1980252 | 0.65 | ADORA3 (0.52) | ADORA2AADORA3SLC28A1PI4KAPI4K2B | |
| SCHEMBL10647704 | 0.64 | PI4K2A (0.51) | ADORA2AADORA3SLC28A1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304889-A2 | Novel aristeromycin/adenosine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-03-01 | — | — | EP | claimed |
| EP-0304889-A2 | Novel aristeromycin/adenosine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1989-03-01 | — | — | EP | disclosed |