Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090846 | 0.89 | ALDH1A1 (0.64) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL317536 | 0.86 | ALDH1A1 (0.66) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL2967753 | 0.86 | HPSE (0.56) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL31090813 | 0.86 | HPSE (0.56) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL28317468 | 0.86 | HSPB1 (0.72) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL20855342 | 0.86 | S1PR4 (0.73) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL810817 | 0.85 | ALDH1A1 (0.65) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL25518718 | 0.85 | ALDH1A1 (0.64) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL15509277 | 0.85 | TSHR (0.60) | TSHRCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL10423773 | 0.84 | MEN1 (0.53) | TSHRCYP3A4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495425-A2 | Preparation of diphenyl ether | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-07-22 | — | — | EP | disclosed |
| US-5117002-A | PREPARATION OF DIPHENYL ETHER | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-05-26 | — | — | US | disclosed |