Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654191 | 0.89 | PDE7A (0.63) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL17428655 | 0.86 | S1PR4 (0.59) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL9687621 | 0.86 | TSHR (0.64) | S1PR4LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL10756271 | 0.84 | S1PR4 (0.56) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL18184327 | 0.83 | S1PR4 (0.56) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL1340557 | 0.82 | HSPB1 (0.56) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL10387432 | 0.82 | PDE7A (0.71) | S1PR4LMNASMN1; SMN2POLBPDE7A | |
| SCHEMBL30392319 | 0.82 | HPGD (0.73) | S1PR4LMNAPDE7ATDP1TSHR | |
| SCHEMBL640965 | 0.82 | HPGD (0.73) | S1PR4LMNAPDE7ATDP1TSHR | |
| SCHEMBL4965836 | 0.81 | MAPK1 (0.62) | S1PR4LMNASMN1; SMN2POLBPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019062802-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION | DONGGUAN HEC TECH R & D CO., LTD. (CN) | 2019-04-04 | — | — | WO | disclosed |