Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635334 | 0.82 | NPSR1 (0.50) | NPSR1CYP1A2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL8691333 | 0.81 | POLB (0.44) | SMN1; SMN2RAB9AALDH1A1MAPTHTT | |
| SCHEMBL23120213 | 0.76 | SMN1; SMN2 (0.66) | NPSR1CYP1A2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL29663590 | 0.76 | SMN1; SMN2 (0.66) | NPSR1CYP1A2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL28882452 | 0.76 | DRD2 (0.34) | DRD2IMPDH2IMPDH1 | |
| SCHEMBL6037914 | 0.75 | MAPT (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL17603155 | 0.72 | GRM4 (0.43) | SMN1; SMN2NPC1HTT | |
| SCHEMBL8479760 | 0.71 | ALDH1A1 (0.50) | NPSR1CYP1A2CYP2C19SMN1; SMN2NPC1 | |
| SCHEMBL6804381 | 0.71 | MAPT (0.50) | NPSR1SMN1; SMN2DRD2ALDH1A1MAPT | |
| SCHEMBL5866568 | 0.71 | ALDH1A1 (0.52) | NPSR1CYP1A2CYP2C19SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |