Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR3 | O15455 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688399 | 0.84 | MAOB (0.69) | MAOBMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL8356708 | 0.81 | NPC1 (0.64) | GSK3BMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29935714 | 0.79 | CTSV (0.56) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL273831 | 0.79 | CTSV (0.56) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8759755 | 0.78 | MAPT (0.55) | GSK3BMAOBMAPTSMN1; SMN2LMNA | |
| SCHEMBL73490 | 0.77 | GSK3B (1.00) | GSK3BLMNA | |
| SCHEMBL21436905 | 0.75 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL23000101 | 0.75 | MAOB (0.47) | GSK3BMAOBMAPTSMN1; SMN2LMNA | |
| SCHEMBL12112515 | 0.74 | MRGPRX4 (0.74) | GSK3BMAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL9687632 | 0.74 | MAPT (0.67) | MAOBMAPTSMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |