Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687655 | 0.84 | GSK3B (0.60) | MAOBMAOAMAPTSMN1; SMN2LMNA | |
| SCHEMBL3123036 | 0.80 | MAOB (0.64) | MAOBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8983023 | 0.79 | SMN1; SMN2 (0.57) | MAOBMAOAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29368594 | 0.77 | ALDH1A1 (0.63) | MAOBMAOAMAPTLMNANPC1 | |
| SCHEMBL965943 | 0.77 | ALDH1A1 (0.63) | MAOBMAOAMAPTLMNANPC1 | |
| SCHEMBL4944452 | 0.77 | KMT2A (0.62) | MAOBMAOAMAPTSMN1; SMN2LMNA | |
| SCHEMBL9687632 | 0.76 | MAPT (0.67) | MAOBMAPTSMN1; SMN2LMNANPC1 | |
| Bicarbonate SCHEMBL5503301 | 0.75 | CYP19A1 (0.65) | MAPTNPSR1CYP19A1 | |
| SCHEMBL12381203 | 0.75 | CYP19A1 (0.68) | MAPTSMN1; SMN2LMNANPC1NFKB1 | |
| SCHEMBL11188627 | 0.74 | MRGPRX4 (0.60) | MAPK1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |