SCHEMBL9687683

SCHEMBL9687683

CCC(=O)Nc1cccc(C)c1CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.46
ALOX12 P18054 1/20 0.46
MAPT P10636 4/20 0.46
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC1 Q13547 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9686578 0.85 HPGD (0.45) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL8175962 0.84 RAB9A (0.46) HPGDALOX12HDAC3HDAC4HDAC1
SCHEMBL9687520 0.83 ALDH1A1 (0.61) HPGDRAB9AALDH1A1SMN1; SMN2POLB
SCHEMBL9694548 0.81 HPGD (0.47) HPGDMAPTRAB9AALDH1A1HSD17B10
SCHEMBL9686214 0.81 POLB (0.51) HPGDALOX12MAPTRAB9AALDH1A1
SCHEMBL10436820 0.81 HDAC3 (0.64) HPGDMAPTHDAC3HDAC4HDAC1
SCHEMBL9686499 0.81 ALDH1A1 (0.57) HPGDMAPTRAB9AALDH1A1SMN1; SMN2
SCHEMBL12408064 0.80 MAPT (0.51) HPGDMAPTHDAC3HDAC4HDAC1
SCHEMBL1818573 0.80 HPGD (0.68) HPGDALOX12MAPTHDAC3HDAC4
SCHEMBL30738307 0.80 HPGD (0.68) HPGDALOX12MAPTHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268989-B1 IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-07-08 EP disclosed
US-4831041-A ANTIULCER AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-05-16 US disclosed
EP-0268989-A1 Imidazopyridine compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-01 EP disclosed