Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9687700 | 0.78 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1KDM4ETSHRALDH1A1 | |
| SCHEMBL19121851 | 0.76 | ACHE (0.41) | CYSLTR2CYSLTR1ACHEBCHEFAAH | |
| SCHEMBL18713464 | 0.75 | HDAC4 (0.49) | ACHEBCHEFAAHRXRARXRB | |
| SCHEMBL18713611 | 0.75 | ACHE (0.43) | ACHEBCHEFAAHMARK4RXRA | |
| Hydrochloric Acid SCHEMBL9687695 | 0.75 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1KDM4ETSHRALDH1A1 | |
| SCHEMBL2737262 | 0.74 | KDM4E (0.49) | ACHEBCHEFAAHRXRARXRB | |
| SCHEMBL9688640 | 0.73 | HIF1A (0.46) | CYSLTR2CYSLTR1ACHEKDM4ETSHR | |
| SCHEMBL6055399 | 0.73 | L3MBTL1 (0.47) | CYSLTR2CYSLTR1ACHEBCHEFAAH | |
| SCHEMBL9689538 | 0.73 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1KDM4ETSHRALDH1A1 | |
| SCHEMBL6055487 | 0.72 | LMNA (0.50) | ACHEBCHEFAAHMARK4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |