Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 14/20 | 0.54 |
| ▸ | NPC1 | O15118 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709071 | 0.87 | NPC1 (0.64) | FGFR1RAB9ANPC1MAPTPKM | |
| SCHEMBL709072 | 0.87 | NPC1 (0.64) | FGFR1RAB9ANPC1MAPTPKM | |
| SCHEMBL19119423 | 0.82 | ALDH1A1 (0.63) | RAB9ANPC1MAPTPKMGAA | |
| SCHEMBL1086985 | 0.74 | ALDH1A1 (0.81) | RAB9ANPC1MAPTPKMGAA | |
| SCHEMBL1086983 | 0.74 | ALDH1A1 (0.81) | RAB9ANPC1MAPTPKMGAA | |
| SCHEMBL29539476 | 0.74 | ALDH1A1 (0.81) | RAB9ANPC1MAPTPKMGAA | |
| Quinoline SCHEMBL27617889 | 0.71 | ALDH1A1 (0.53) | FGFR1RAB9ANPC1MAPTPKM | |
| SCHEMBL41190 | 0.71 | RAB9A (0.74) | RAB9ANPC1PKMALDH1A1KMT2A | |
| SCHEMBL3081168 | 0.71 | ALDH1A1 (0.59) | RAB9ANPC1MAPTPKMGAA | |
| SCHEMBL376644 | 0.71 | ALDH1A1 (0.59) | RAB9ANPC1MAPTPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201575-B1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-08-12 | — | — | EP | claimed |
| EP-0166287-B1 | DIALKOXYRIDINES, PROCESS FOR THEIR PREPARATION, THEIR APPLICATION AND MEDICAMENTS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-08-23 | — | — | EP | claimed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |