Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 4/20 | 0.37 |
| ▸ | ATP4B | P51164 | 4/20 | 0.37 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530579 | 0.87 | ATP4A (0.40) | TDP1ATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL9531757 | 0.84 | ATP4A (0.48) | MEN1KMT2ATDP1ATP4AATP4B | |
| SCHEMBL9528285 | 0.83 | ATP4A (0.43) | ATP4AATP4BATP1A1ATP1B1ATP1A3 | |
| SCHEMBL1007193 | 0.76 | FABP6 (0.59) | ATMMEN1MAPTKMT2APSMD14 | |
| SCHEMBL9687854 | 0.75 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9455942 | 0.74 | AMY1A (0.47) | ATMMEN1MAPTKMT2APSMD14 | |
| SCHEMBL10844887 | 0.72 | MAPT (0.50) | ATMMEN1MAPTKMT2APSMD14 | |
| SCHEMBL482378 | 0.72 | NPC1 (0.41) | MEN1MAPTKMT2AATP4AATP4B | |
| SCHEMBL2108226 | 0.72 | CYP3A4 (0.49) | MEN1MAPTKMT2AATP4AATP4B | |
| SCHEMBL211457 | 0.72 | AMY1A (0.45) | MEN1KMT2AAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201575-B1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0201575-A1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1986-11-20 | — | — | EP | disclosed |
| WO-1986002646-A1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT M (DE) | 1986-05-09 | — | — | WO | disclosed |