SCHEMBL9688078

SCHEMBL9688078

c1ccc2sc(SSSN3CCOCC3)nc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.71
HSD17B10 Q99714 3/20 0.71
HPGD P15428 2/20 0.71
ALOX15 P16050 2/20 0.71
PKM P14618 2/20 0.71
KDM4E B2RXH2 1/20 0.71
FBP1 P09467 3/20 0.55
ADRA2A P08913 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
DRD2 P14416 1/20 0.55
ADRA2B P18089 1/20 0.55
ADRA2C P18825 1/20 0.55
DRD1 P21728 1/20 0.55
MC5R P33032 1/20 0.55
OPRM1 P35372 1/20 0.55
DRD3 P35462 1/20 0.55
OPRK1 P41145 1/20 0.55
CCR2 P41597 1/20 0.55
HTR6 P50406 1/20 0.55
SLC6A3 Q01959 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392402 0.92 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL637062 0.92 ALDH1A1 (0.74) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL25278796 0.84 NPC1 (0.71) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL29404281 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL79658 0.83 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11882398 0.81 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL28167550 0.81 ALDH1A1 (0.66) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL11873171 0.79 ALDH1A1 (0.64) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL6915262 0.77 ALDH1A1 (0.69) ALDH1A1HSD17B10HPGDALOX15PKM
SCHEMBL8516465 0.77 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDALOX15PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602917-B Method for in-situ isomerization of polybutadiene 米其林集团总公司 2021-06-29 CN disclosed
US-5124450-A Reacting solution of 2-mercaptothiazole, saturated secondary heterocyclic amine, sulfur in presence of oxygen, ammonia, copper or cerium catalyst AKZO N.V. (NL) 1992-06-23 US disclosed
EP-0481366-A1 Process for the preparation of 2-Aminodithiothiazoles and 2-Aminotrithiothiazoles Akzo Nobel N.V. (NL) 1992-04-22 EP disclosed