Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688582 | 0.81 | SLC18A2 (0.61) | SLC18A2 | |
| Hydrochloric Acid SCHEMBL9689390 | 0.80 | SLC18A2 (0.59) | SLC18A2 | |
| SCHEMBL9688093 | 0.72 | CHRNB2 (0.47) | — | |
| SCHEMBL9688095 | 0.72 | CHRNB2 (0.47) | — | |
| SCHEMBL9688088 | 0.72 | CHRNB2 (0.47) | — | |
| SCHEMBL13660514 | 0.72 | CHRNB2 (0.49) | — | |
| SCHEMBL3878986 | 0.70 | HSD11B1 (0.74) | SLC18A2HSD11B1 | |
| SCHEMBL581718 | 0.70 | SLC18A2 (0.50) | SLC18A2 | |
| SCHEMBL20005917 | 0.69 | CYP3A4 (0.45) | — | |
| SCHEMBL6420430 | 0.69 | SLC18A2 (0.46) | SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237169-B1 | 5-SUBSTITUTED OCTAHYDROINDOLIZINE ANALGESICS COMPOUNDS AND 7-KETO INTERMEDIATES | McNeilab, Inc. (US) | 1992-07-08 | — | — | EP | claimed |
| EP-0237169-A1 | 5-Substituted octahydroindolizine analgesics compounds and 7-keto intermediates | McNeilab, Inc. (US) | 1987-09-16 | — | — | EP | claimed |
| EP-0237169-B1 | 5-SUBSTITUTED OCTAHYDROINDOLIZINE ANALGESICS COMPOUNDS AND 7-KETO INTERMEDIATES | McNeilab, Inc. (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0237169-A1 | 5-Substituted octahydroindolizine analgesics compounds and 7-keto intermediates | McNeilab, Inc. (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4689329-A | 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates | MCNEILAB, INC. (US) | 1987-08-25 | — | — | US | disclosed |