Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689459 | 0.89 | ALDH1A1 (0.33) | ALDH1A1MAPTPOLB | |
| SCHEMBL3936524 | 0.75 | MAPT (0.38) | ALDH1A1MAPTPOLB | |
| SCHEMBL4869101 | 0.72 | MAPT (0.35) | ALDH1A1MAPTPOLB | |
| SCHEMBL9690293 | 0.71 | DAO (0.37) | ALDH1A1MAPTPOLB | |
| SCHEMBL15163818 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLB | |
| SCHEMBL21651113 | 0.71 | DAO (0.37) | ALDH1A1MAPTPOLB | |
| SCHEMBL3505646 | 0.71 | GPR84 (0.40) | — | |
| SCHEMBL26983541 | 0.70 | — | — | |
| SCHEMBL3938297 | 0.70 | — | — | |
| SCHEMBL4022760 | 0.69 | ALDH1A1 (0.36) | ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |
| EP-0358676-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0293078-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1988-11-30 | — | — | EP | disclosed |
| WO-1988008424-A1 | PHARMACEUTICALLY ACTIVE AMINES | THE UPJOHN COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |