Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688152 | 0.89 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLB | |
| SCHEMBL4869101 | 0.77 | MAPT (0.35) | ALDH1A1MAPTPOLB | |
| SCHEMBL3505646 | 0.76 | GPR84 (0.40) | HIF1A | |
| SCHEMBL9690293 | 0.76 | DAO (0.37) | ALDH1A1MAPTPOLB | |
| SCHEMBL3387307 | 0.74 | ALOX5 (0.36) | ALDH1A1MAPTPOLB | |
| SCHEMBL3387146 | 0.74 | ALOX5 (0.36) | ALDH1A1MAPTPOLB | |
| SCHEMBL3388547 | 0.74 | ALOX5 (0.36) | ALDH1A1MAPTPOLB | |
| SCHEMBL3388090 | 0.74 | ALOX5 (0.36) | ALDH1A1MAPTPOLB | |
| SCHEMBL3387143 | 0.74 | ALOX5 (0.36) | ALDH1A1MAPTPOLB | |
| SCHEMBL6282240 | 0.74 | GPR84 (0.42) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |