SCHEMBL9688485

SCHEMBL9688485

CCCCCCCc1ccc(-c2ccc(C(CC)OCCC)c(C(=O)O)c2-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.44
RARA P10276 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
MTOR P42345 1/20 0.43
KMT2A Q03164 1/20 0.43
EP300 Q09472 1/20 0.40
KAT5 Q92993 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
RARG P13631 1/20 0.39
MGLL Q99685 1/20 0.38
PPARA Q07869 1/20 0.38
PLK1 P53350 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797753 0.78 KAT8 (0.47) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL9689012 0.77 RARB (0.64) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL6883429 0.75 RARB (0.59) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL11815595 0.70 RARB (0.59) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL9688532 0.70 RARB (0.54) RARB
SCHEMBL6865795 0.70 RARB (0.54) RARBRARAMEN1ALDH1A1MAPT
Bicarbonate SCHEMBL27643232 0.69 RARB (0.73) RARBRARAMEN1ALDH1A1MAPT
Bicarbonate SCHEMBL27817579 0.69 RARB (0.73) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL16678699 0.69 HSD11B1 (0.63) RARBRARAMEN1ALDH1A1MAPT
SCHEMBL11634681 0.68 ALDH1A1 (0.58) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5167857-A Optically active, optical modulation CANON KABUSHIKI KAISHA (JP) 1992-12-01 US claimed
EP-0175591-B1 LACTIC ACID DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed
EP-0175591-A2 Lactic acid derivative, liquid crystal composition containing same and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1986-03-26 EP claimed
US-5167857-A Optically active, optical modulation CANON KABUSHIKI KAISHA (JP) 1992-12-01 US disclosed
EP-0175591-B1 LACTIC ACID DERIVATIVE, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE CANON KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
US-4775223-A DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 1988-10-04 US disclosed