Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688581 | 0.92 | KMT2A (0.45) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690589 | 0.89 | MEN1 (0.42) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690654 | 0.89 | MAPT (0.55) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690661 | 0.89 | MAPT (0.55) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690586 | 0.89 | MEN1 (0.42) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690004 | 0.79 | SARM1 (0.40) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690057 | 0.77 | KDM4E (0.38) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690064 | 0.77 | KDM4E (0.38) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690756 | 0.76 | KMT2A (0.34) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9690760 | 0.76 | KMT2A (0.34) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |