Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690008 | 1.00 | SARM1 (0.40) | SARM1KMT2AMEN1MAPTHTT | |
| SCHEMBL9690672 | 0.81 | KMT2A (0.50) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9690756 | 0.81 | KMT2A (0.34) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9690760 | 0.81 | KMT2A (0.34) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9690586 | 0.81 | MEN1 (0.42) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9690589 | 0.81 | MEN1 (0.42) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL10841304 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL10841300 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9688581 | 0.79 | KMT2A (0.45) | KMT2AMEN1MAPTHTTGAA | |
| SCHEMBL9688567 | 0.79 | KMT2A (0.45) | KMT2AMEN1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |