Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690760 | 1.00 | KMT2A (0.34) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690004 | 0.81 | SARM1 (0.40) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690008 | 0.81 | SARM1 (0.40) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690672 | 0.81 | KMT2A (0.50) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL10841304 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL10841300 | 0.80 | ALDH1A1 (0.46) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690589 | 0.78 | MEN1 (0.42) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690550 | 0.78 | SIGMAR1 (0.36) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690586 | 0.78 | MEN1 (0.42) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL9690661 | 0.78 | MAPT (0.55) | KMT2AMEN1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |