Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687977 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL9688878 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL364241 | 0.76 | HPGD (0.56) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL9687817 | 0.74 | HPGD (0.46) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL16953911 | 0.73 | KMT2A (0.56) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL13689273 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL14490203 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL5139133 | 0.72 | HPGD (0.68) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL13753371 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL9043907 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |