Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687402 | 0.86 | CES2 (0.50) | ALDH1A1MAPTTP53RAB9ANPC1 | |
| SCHEMBL9247753 | 0.77 | SMN1; SMN2 (0.46) | HPGDKMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9686785 | 0.77 | ESR1 (0.45) | LMNAALDH1A1CYP3A4KDM4EHSD17B10 | |
| SCHEMBL364241 | 0.77 | HPGD (0.56) | HPGDKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9687977 | 0.76 | ALDH1A1 (0.48) | HPGDKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL16953911 | 0.74 | KMT2A (0.56) | HPGDKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9688568 | 0.74 | ALDH1A1 (0.49) | HPGDKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9688878 | 0.74 | ALDH1A1 (0.46) | HPGDKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL28098734 | 0.74 | ESR1 (0.56) | HPGDLMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5139133 | 0.73 | HPGD (0.68) | HPGDKMT2ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136114-A | PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |