Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223066 | 0.85 | PRKAB2 (0.39) | ADORA2AADORA3HSP90B1PRKAB2PRKAG1 | |
| SCHEMBL9689709 | 0.78 | ABCB1 (0.38) | ADORA2AADORA3LMNA | |
| SCHEMBL6223064 | 0.78 | PRKAB2 (0.46) | ADORA2AADORA3HSP90B1PRKAB2PRKAG1 | |
| SCHEMBL9689114 | 0.76 | ADORA2A (0.36) | ADORA2AADORA3RXFP1PI4KAPI4K2B | |
| SCHEMBL6222357 | 0.74 | ADORA2A (0.50) | ADORA2AADORA3HSP90B1AHCYRXFP1 | |
| SCHEMBL9689115 | 0.73 | ADORA3 (0.42) | ADORA2AADORA3AHCY | |
| SCHEMBL2955999 | 0.72 | BCHE (0.42) | ADORA3HSP90B1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6221610 | 0.72 | ADORA2A (0.47) | ADORA2AADORA3PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL25408738 | 0.72 | ADORA2A (0.52) | ADORA2AADORA3HSP90B1AHCYRXFP1 | |
| SCHEMBL9620171 | 0.72 | ALDH1A1 (0.40) | ADORA2APRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493602-A1 | PROCESS FOR PRODUCING 2',3'-DIDEOXY-2',3'-DIDEHYDRONUCLEOSIDE | YUKI GOSEI KOGYO CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |