Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811246 | 0.82 | CA2 (0.57) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL15714465 | 0.78 | ALDH1A1 (1.00) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL130491 | 0.75 | KDM4E (0.74) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL16369640 | 0.74 | ALDH1A1 (0.62) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL3140547 | 0.73 | ALDH1A1 (0.67) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL1786657 | 0.73 | POLB (0.62) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL9661958 | 0.73 | PKM (0.60) | HSD17B10POLBKDM4EALDH1A1CYP2C9 | |
| SCHEMBL7538066 | 0.73 | CA2 (0.53) | HSD17B10KDM4EALDH1A1HPGDCYP2C9 | |
| SCHEMBL1725851 | 0.71 | CSNK2A1 (0.53) | HSD17B10POLBKDM4EALDH1A1HPGD | |
| SCHEMBL10743411 | 0.71 | CA1 (0.56) | HSD17B10KDM4EALDH1A1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5127937-A | N-SUBSTITUTED-3-(NITROGEN-CONTAINING 5-MEMBERED RING)-BENZENESULFONAMIDE DERIVATIVES, AND HERBICIDAL COMPOSITIONS | KUREHA KAGAKU KOGYO K.K. (JP) | 1992-07-07 | — | — | US | disclosed |