Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9689743 | 0.80 | CYSLTR1 (0.64) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL9688764 | 0.79 | CYSLTR2 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL9688226 | 0.78 | CYSLTR1 (0.45) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL9689538 | 0.78 | CYSLTR2 (0.49) | ALOX5CYSLTR2CYSLTR1TLR4TLR2 | |
| Hydrochloric Acid SCHEMBL9688773 | 0.77 | CYSLTR1 (0.44) | ALOX5CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL9688361 | 0.77 | CYSLTR2 (0.48) | ALOX5CYSLTR2CYSLTR1TLR4TLR2 | |
| SCHEMBL10656521 | 0.77 | ALOX5 (0.69) | ALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL10434840 | 0.75 | ALOX5 (0.56) | ALOX5 | |
| Dimethylamine SCHEMBL9687700 | 0.75 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1 | |
| SCHEMBL9689101 | 0.75 | CYSLTR1 (0.42) | ALOX5CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291916-B1 | DITHIOACETAL COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5081126-A | QUINOLYL- AND ISOQUINOLYL-METHOXYPHENYL-DITHIOACETYL DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4963576-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; 5-LIPOXYGENASE INHIBITOR | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0291916-A1 | Dithioacetal compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |