Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | ACACB | O00763 | 6/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | ACACA | Q13085 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688646 | 1.00 | DRD2 (0.63) | DRD2ACACBNAMPTACACAADRA1D | |
| SCHEMBL9133081 | 0.85 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9362314 | 0.85 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9134300 | 0.85 | DRD2 (0.47) | DRD2ACACBNAMPTACACA | |
| SCHEMBL9361441 | 0.85 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9689056 | 0.84 | DRD2 (0.49) | DRD2ACACBNAMPTACACACKS1B | |
| SCHEMBL12635377 | 0.84 | DRD2 (0.52) | DRD2ACACBNAMPTACACAADRA1A | |
| SCHEMBL6194968 | 0.83 | DRD2 (0.46) | DRD2ACACBNAMPTACACAADRA1D | |
| SCHEMBL12635376 | 0.83 | MTNR1A (0.52) | DRD2MTNR1AMTNR1B | |
| SCHEMBL5548043 | 0.82 | DRD2 (0.45) | DRD2ACACBNAMPTACACACKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |