Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | ACACB | O00763 | 10/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 6/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688829 | 0.84 | DRD2 (0.63) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL9688646 | 0.84 | DRD2 (0.63) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL9361441 | 0.80 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9362314 | 0.80 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9133081 | 0.80 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL431869 | 0.79 | EPHX2 (0.46) | DRD2KMT2A | |
| SCHEMBL9134300 | 0.77 | DRD2 (0.47) | DRD2ACACBACACANAMPT | |
| SCHEMBL9132660 | 0.77 | DRD2 (0.47) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL9132051 | 0.76 | DRD2 (0.47) | DRD2ACACBCKS1BSKP1SKP2 | |
| SCHEMBL6194968 | 0.75 | DRD2 (0.46) | DRD2ACACBCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |