Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243215 | 0.89 | MAOA (0.55) | MAOAMAOBBAZ2BBRD4CYP2A6 | |
| SCHEMBL8318501 | 0.80 | MAOA (0.53) | MAOAMAOBBAZ2BBRD4CYP2A6 | |
| SCHEMBL9175124 | 0.80 | MAOA (0.40) | MAOAMAOBBAZ2BCYP2A6PRKCI | |
| SCHEMBL30957744 | 0.80 | MAOA (0.48) | MAOAMAOBBAZ2BBRD4CYP2A6 | |
| SCHEMBL9688253 | 0.79 | MAOA (0.57) | MAOAMAOBBAZ2BBRD4CYP2A6 | |
| SCHEMBL10631228 | 0.76 | MAOA (0.55) | MAOAMAOBBAZ2BBRD4CYP2A6 | |
| SCHEMBL19132364 | 0.74 | MAOA (0.50) | MAOAMAOBBRD4CYP2A6PBRM1 | |
| SCHEMBL120284 | 0.74 | MAOB (0.58) | MAOAMAOBCYP2A6HRH3ACHE | |
| SCHEMBL29726357 | 0.74 | MAOB (0.58) | MAOAMAOBCYP2A6HRH3ACHE | |
| SCHEMBL9027437 | 0.73 | MAOB (0.49) | MAOAMAOBBAZ2BBRD4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517065-A1 | Tetracyclic beta-lactam antibiotics and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-09 | — | — | EP | disclosed |