Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 12/20 | 0.75 |
| ▸ | AGTR1 | P30556 | 11/20 | 0.75 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194373 | 0.86 | AGTR1 (1.00) | AGTR2AGTR1 | |
| SCHEMBL9197814 | 0.84 | AGTR1 (0.81) | AGTR2AGTR1KDM4E | |
| SCHEMBL7054450 | 0.83 | AGTR2 (0.71) | AGTR2AGTR1 | |
| SCHEMBL1160061 | 0.78 | PPARG (0.47) | AGTR2AGTR1ALDH1A1 | |
| SCHEMBL7591162 | 0.77 | AGTR2 (0.62) | AGTR2AGTR1 | |
| SCHEMBL8394993 | 0.75 | AGTR2 (0.76) | AGTR2AGTR1 | |
| SCHEMBL1159879 | 0.74 | AGTR2 (0.58) | AGTR2AGTR1 | |
| Hydrochloric Acid SCHEMBL9137606 | 0.73 | AGTR1 (0.61) | AGTR2AGTR1 | |
| SCHEMBL9687841 | 0.73 | AGTR1 (0.72) | AGTR2AGTR1 | |
| SCHEMBL8394534 | 0.72 | PPARG (0.77) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171748-A | For hypertension, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-15 | — | — | US | disclosed |