Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690370 | 0.89 | EGFR (0.42) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL9690330 | 0.85 | MEN1 (0.42) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL9690098 | 0.78 | HSD17B10 (0.44) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL9689731 | 0.78 | HSD17B10 (0.48) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL6656429 | 0.77 | HSD17B10 (0.56) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL27600329 | 0.76 | GSK3B (0.44) | KDM4EHSD17B10ALDH1A1HPGDKMT2A | |
| SCHEMBL9689797 | 0.74 | GABRP (0.68) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL6650935 | 0.72 | ACHE (0.42) | HSD17B10TP53 | |
| SCHEMBL8809770 | 0.70 | NR4A2 (0.49) | KDM4EHSD17B10ALDH1A1HPGDMEN1 | |
| SCHEMBL27618833 | 0.69 | EGFR (0.54) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249301-B1 | Pyrido[2,3-b]indoles | BEECHAM GROUP PLC (GB) | 1992-05-27 | — | — | EP | claimed |