Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP4 | P49662 | 4/20 | 0.44 |
| ▸ | CASP5 | P51878 | 4/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690143 | 0.84 | HRH1 (0.40) | CASP1CASP4CASP5HRH4HRH1 | |
| SCHEMBL9688175 | 0.81 | CASP1 (0.51) | CASP1CASP4CASP5HRH4HRH1 | |
| Hydrochloric Acid SCHEMBL9690244 | 0.80 | CASP1 (0.50) | CASP1CASP4CASP5HRH4HRH1 | |
| SCHEMBL9689126 | 0.74 | SLC6A4 (0.37) | TDP1MAPT | |
| SCHEMBL9690206 | 0.73 | CASP1 (0.48) | CASP1CASP4CASP5HRH4HRH1 | |
| Hydrochloric Acid SCHEMBL9689568 | 0.72 | CASP1 (0.47) | CASP1CASP4CASP5HRH4HRH1 | |
| SCHEMBL9689160 | 0.71 | CASP1 (0.46) | CASP1CASP4CASP5HRH4HRH1 | |
| SCHEMBL9689542 | 0.71 | CASP1 (0.46) | CASP1CASP4CASP5HRH4HRH1 | |
| Hydrochloric Acid SCHEMBL9690260 | 0.70 | CASP1 (0.45) | CASP1CASP4CASP5HRH4HRH1 | |
| Hydrochloric Acid SCHEMBL9689164 | 0.70 | CASP1 (0.45) | CASP1CASP4CASP5HRH4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487510-A1 | Pharmaceutically active amines | THE UPJOHN COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |